Saturday 03.11.2007

Scientific Session Satellite Symposium Main Program Workshop
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Session details 14:00–15:30
Workshop 1 (Parallel Sessions)

Cancer Survivorship

Room:Pipin II (Dorint Hotel)
  • Myocardial Infarction Mortality Risk after Treatment for HL: a Collaborative British Cohort Study

  • Risk Factors for Cardiovascular Disease; Dutch Results

  • Clinical Applications of Modelled Second Cancer Risk Among HL Survivors

  • Breast Tumors Induced by High-dose Radiation Display Similar Genetic Profiles

  • Screening for Lung Cancer in Patients at High Risk of this Second Cancer after Treatment for HL

  • Breast Cancer Screening with MRI in Female HL Survivors

Session details 14:00–15:30
Workshop 2 (Parallel Sessions)

Pathology

Room:Pipin I (Dorint Hotel)
  • Cytokine Gene Expression and T-Cell Transcription Factor Profile of the T-Cells of the Nodular Lymphocyte Predominance Type of HL

  • Double-Positive CD4+CD8+ T-Cell Populations in Nodular Lymphocyte Predominant HL: Further Characterization and Relationship to Other Entities

  • CD4/CD8-double Positive T-Cells in Nodular Lymphocyte Predominance HL

  • Regulatory T-Cells in Classical HL

  • Biologic Prognostic Markers in cHL: Evaluation of Characteristics of RS Cells as well as the Tumor Infiltrating Lymphocytes

  • dentification and Purification of Hodgkin Cells from Lymph Nodes Involved by Classical HL by Flow Cytometry and Flow Cytometric Cell Sorting

Session details 14:00–15:30
Workshop 3 (Parallel Sessions)

Allogeneic Stem Cell Transplantation

Room:Martin & Augustin (Dorint Hotel)
  • Allogeneic Hematopoietic Cell Transplantation for HL

  • Allogeneic Stem Cell Transplantation (Allo-SCT) in HL: The European Point of View

  • Improved Outcome Following Reduced Intensity Allogeneic Transplantation in HL Relapsing Post-Autologous Transplantation

  • Allogeneic/Syngeneic/Autologous Transplantation – a Comparison

Session details 14:00–15:30
Workshop 4 (Parallel Sessions)

Pædiatric Hodgkin Lymphoma

Room:Severin (Dorint Hotel)
  • Current Protocols and Concepts in the USA

  • Strategy of the EuroNet-PHL-C1 Protocol for the Treatment of Classical HL in Children and Adolescents

  • First International Inter-Group Study for Lymphocyte Predominant HL in Children and Adolescents

  • Current Children’s Oncology Group (COG) Protocol for LPHL

Session details 16:00–17:30
Workshop 5

Future Studies / Intergroup Trials

Room:Pipin II (Dorint Hotel)
  • The new trial generation of the German Hodgkin Study Group (GHSG)

  • The H10 EORTC/GELA Randomized Intergroup Trial on Early FDG-PET Scan Guided Treatment Adaptation Versus Standard Combined Modality Treatment in Patients with Supradiaphragmatic Stage I/II HL

  • Response-Adapted Therapy Using FDG-PET Scanning after Initial ABVD: The UK NCRI, Italian and Nordic Trial in Advanced HL

  • Identification of Relevant and Practical Questions for an Transatlantic Intergroup Designs

  • Development of ABVD as Standard Treatment for HL

  • Organisation Central On-line PET Review

Session details 16:00–18:00
Scientific Session 1

Chronic Inflammation

Room:Isabellensaal

Sunday 04.11.2007

Scientific Session Satellite Symposium Main Program Workshop
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Session details 08:30–10:00
Scientific Session 2

Characterization of HRS Cells and "Stem Cells" in HL

Room:Großer Saal
  • Molecular Immunogenetics of B Cells and HRS Cells

  • Translocations in HRS Cells

  • The Plasticity of HRS Cells

  • The Role of microRNA for Regulation of PRDM1/Blimp-1in HRS Cells

  • BIC and other miRNAs in HL

  • HL: Evidence for a Cancer Stem Cell and Therapeutic Implications

  • Induction of Hodgkin-like Phenotype by Epigenetic Reprogramming of B Cells

  • 3D Nuclear Organization of Telomeres in HRS Cells

Session details 10:30–12:00
Scientific Session 3

Scientific Session on Translational Approaches

Room:Großer Saal
  • Antiangiogenic Agents

  • KLHDC8B: a Candidate HL Susceptibility Gene

  • Analysis of Genetic Predisposition to Hematotoxicity in HL

  • Serum Profiling of Cytokines

  • Targeted Treatment Approaches in HL

  • How to Select Novel Small Molecules for Early Clinical Testing

  • Proteomics Analysis of HL: Identification of New Players Involved in the Cross Talk between HRS Cells and Infiltrating Lymphocytes

  • Galectin 1 Mediates Tumor Escape in HL

Session details 12:15–13:45
Satellite Symposium

Prophylaxis and Treatment of Side Effects of Chemotherapy: Casuistic Forum

Room:Großer Saal
Session details 14:00–15:30
Satellite Symposium

Innovative Strategies in the Therapy of Hematological Malignancies

Room:Großer Saal
  • Velcade – Lead Compound in Multiple Myeloma?

  • Future Directions in the Treatment of MDS

  • Velcade – Innovative Therapy Options in NHL

  • Efficient Hb Management in Lymphoma: Results of the HD15 Protocol

Session details 16:00–17:30
Satellite Symposium

Treatment of Lymphomas: Current Strategies and Future Outlook

Room:Großer Saal
  • Pathogenesis of B-Cell Lymphomas and Identification of Molecules Suitable for Targeted Therapy

  • Review of Immuno-Chemotherapy in Aggressive and Follicular Lymphoma

  • State of the Art Therapy Non Hodgkin Lymphoma in the USA

  • Role of Immuno-Chemotherapy in HL

  • New treatment approaches in Aggressive Lymphoma: Intensified Immuno-Chemotherapy - Anti-VEGF + Immuno-Chemotherapy

  • New Treatment Approaches in HL: Emergence of Anti-VEGF as a New Modality in HL

Session details 17:30–20:00
Main Program

Opening Ceremony

Room:Großer Saal
  • From the Absorbent Gland to the “Molecular Cure” of Hodgkin Lymphoma

Session details 20:00
Main Program

Kick-off party

Room:Weinkeller

Monday 05.11.2007

Scientific Session Satellite Symposium Main Program Workshop
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Session details 08:30–10:00
Scientific Session 4

Survivorship

Room:Großer Saal
  • Screening in High Risk Groups

  • Pulmonary and Cardiac Toxicity in HL Survivors

  • How to Preserve Fertility in HL Patients

  • Efficacy and Toxicity of Treatment of HL /Mature Data from a Single Centre

  • Causes of Death and Excess Mortality after HL: the EORTC-GELA Experience

  • Survival Patterns among HL Patients with a Family History of Lymphoma

Session details 10:30–12:00
Scientific Session 5

Early Stage HL

Room:Großer Saal
  • Defining the Role of Radiation Therapy (RT)

  • Chemotherapy Only

  • Combined Modality Approaches

  • Results of the EORTC-GELA H9 Randomized Trials: the H9-F Trial (Comparing 3 Radiation Dose Levels) and H9-U Trial (Comparing 3 Chemotherapy Schemes) in Patients with Favorable or Unfavorable Early Stage HL

  • Stage I/II HL with Bulky Mediastinal Disease or other Risk Factors; The Stanford V Experience

  • Chemotherapy is Essential for Optimal Treatment of Limited Stage Nodular Lymphocyte Predominant HL

Session details 12:15–13:45
Satellite Symposium

Procarbazine: An Established Drug with a New Life

Room:Großer Saal
  • Hodgkin Lymphoma: Better Cure with or without Procarbazine?

  • Therapy of primary CNS-Lymphomas: What’s new?

  • Molecular Predictors and Prognostic Markers in Brain Tumours.

  • What can we learn from Randomized Trials with Patients with Anaplastic Gliomas?

  • Investing in the Future of Cancer Patients

  • Summary and Closing Remarks

Session details 14:00–15:30
Scientific Session 6

Relapsed and Refractory Disease

Room:Großer Saal
  • GHSG Trials in Relapsed HL

  • The Role of Gemcitabine in the Treatment of Primary and Relapsed Disease

  • New Agents

  • Ifosfamide, Gemcitabine, Vinorelbine, Prednisolone (IGEV) and Fixed Dose of Lenograstim: an Effective Mobilization Regimen in Pretreated HL Patients

  • A Phase II Study of MGCD0103, a Novel Oral Isotype-Selective Histone Deacetylase Inhibitor, in Patients with Relapsed or Refractory HL

  • Promising Results for Patients with Relapsed or Refractory HL Treated with the Oral mTOR Inhibitor Everolimus (RAD001)

Session details 16:00–17:30
Scientific Session 7

Translational Research

Room:Großer Saal
  • Biological Risk Factors for Stratification of HL Patients

  • The Role of the Microenvironment in HL

  • Analysing Differential Gene Expression and Genetic Lesions in HRS and L&H Cells to Identify New Therapeutic Targets

  • Latent EBV Infection of HRS Cells Predicts Adverse Outcome in Older Adult Classical HL Patients

  • A Taqman-Low Density Array to Predict Outcome in HL Using Paraffin Embedded Samples

  • Associations between Plasma Levels and Promoter Genotypes of IL-10 and IL-6 with Patient Characteristics and Outcome in HL

Session details 17:30–18:45
Main Program

Key Note Lecture

Room:Großer Saal
  • The Role of Innate Immunity in Cancer Progression

Session details 19:00–20:00
Satellite Symposium

Therapy of HL: Efficacy and Long Term Safety

Room:Großer Saal
  • Glycosylated G-CSF Mobilises More Clonogenic Progentiors than Non-Glycosylated G-CSF

  • Treatment Associated Long Term Toxicity in HL Patients

Tuesday 06.11.2007

Scientific Session Satellite Symposium Main Program Workshop
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Session details 08:30–10:00
Scientific Session 8

Radiotherapy

Room:Großer Saal
  • Dose and Field Size: the EORTC Experience

  • Dose and Field Size: the GHSG Experience

  • Radioimmunotherapy (RIT) Applied to HL – a Useful Tool?

  • Yttrium-90 Radiolabeled Humanized Anti- CD25 Monoclonal Antibody, Daclizumab Provides Effective Therapy for Refractory and Relapsed HL

  • Involved Node Radiotherapy: Impact on Dose to PTV and Organs at Risk

  • Chemotherapy Alone versus Chemotherapy Plus Radiotherapy for Early Stage HL

Session details 10:30–12:00
Scientific Session 9

Allogenetic Transplantation

Room:Großer Saal
  • Overview on Transplantation Strategies

  • Do we Need Allogeneic Transplantation in HL?

  • New Frontiers in Allogeneic Transplantation for HL

  • Reduced Intensity Allogeneic Stem Cell Transplantation (RIC-Allo) for Refractory / Relapsed HL. Preliminary Results of an EBMT Prospective Trial

  • Workshop Report

Session details 12:15–13:45
Satellite Symposium

Role of Gemcitabine in the Treatment of Hodgkins Lymphoma

Room:Großer Saal
Session details 14:00–15:30
Scientific Session 10

PET

Room:Großer Saal
  • PET-CT for Treatment Response Assessment in Lymphoma

  • PET for Early Response Adapted Therapy

  • Current Role and Future of PET in HL

  • FDG-PET for Assessment of Residual Tissue after Completion of Chemotherapy in HL – Report on the 2nd Interim Analysis of the PET Investigation in the Trial HD15 of the GHSG

  • Early Interim FDG-PET Overshadows the Prognostic Role of IPS in Advanced-stage HL Treated by Conventional ABVD Therapy

  • Interim Results of a UK NCRI Randomised Trial Comparing Involved Field Radiotherapy with No Further Treatment after 3 Cycles ABVD and a “Negative” PET Scan in Clinical Stages IA/IIA

Session details 16:00–17:30
Scientific Session 11

Advanced Stages HL

Room:Großer Saal
  • North America: Cooperative Groups

  • EORTC

  • GHSG

  • Phase-II Study of Rituximab Plus ABVD for the Treatment of Newly Diagnosed Patients with Advanced Stage Classical HL

  • High-dose Therapy and ASCT versus Conventional Therapy for Patients with Advanced HL Responding to Front-line Therapy: Long Term Results

  • ABVD vs. COPPEBVCAD (CEC) vs. BEACOPP for the Initial Treatment of Patients with Advanced HL. Preliminary Results of HD2000 GISL Trial

Session details 17:30–18:45
Main Program

Closing Remarks

Room:Großer Saal
Session details 19:00
Main Program

Speakers Dinner

Room:tba

Wednesday 07.11.2007

Scientific Session Satellite Symposium Main Program Workshop
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Session details 08:30–10:00
Workshop 6

For Young Oncologists

Room:tba

Basement

Allocations

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Floor plan of Basement Wardrobe Stair to Ground Floor Stair to Ground Floor Weinkeller Basement

First Floor

Allocations

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Floor plan of First Floor Stair to Ground Floor Stair to Ground Floor Großer Saal Isabellensaal First Floor

Dorint Hotel: Ground Level

Allocations

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Floor plan of Dorint Hotel: Ground Level Stair to Ground Floor Stair to Ground Floor Go to First Floor Pipin II Pipin I Dorint Hotel: Ground Level

Dorint Hotel: First Floor

Allocations

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Floor plan of Dorint Hotel: First Floor Go to Ground Level Martin & Augustin Severin Dorint Hotel: First Floor

Exhibition

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Map of the exhibition. Map of the First Floor showing the location of 0 exhibitors. Stair to Ground Floor Stair to Ground Floor Großer Saal Isabellensaal

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